Medically Reviewed by Brunilda Nazario, MD on October 28, 2025
Practice Medication Safety
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Practice Medication Safety

Any type of medicine you take can come with risks and benefits, including your Parkinson’s disease treatment. Your meds help control your worsening symptoms in later stages of the disease. Here are a few tips to keep you safe:

  1. Take your medicines exactly the way your doctor prescribes.
  2. Read the directions on the label carefully.
  3. Ask questions if you’re unsure.
  4. Talk to your doctor before making any changes.
Keep a Medicine List
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Keep a Medicine List

Make note of every medicine, vitamin, or supplement you’re taking. Carry this list with you each time you see your:

  • Neurologist
  • Movement disorder specialist
  • Any other doctor

You’re unique, and so is your situation. So your doctor may suggest not taking certain medications with Parkinson’s disease. If you need to add another medicine to your list, check with your doctor first. They’ll make sure there aren’t any interactions. 

Watch for Parkinson’s Medication Side Effects
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Watch for Parkinson’s Medication Side Effects

When taken as directed, your Parkinson’s meds can come with more benefits than risks. Everyone is different, but you may get some side effects like:

  • Nausea
  • Feeling lightheaded
  • Involuntary movements
  • Sleepiness
  • Compulsive behaviors
  • Constipation

If you notice any new side effects or bothersome symptoms, tell your doctor right away.

Stick to a Medication Schedule
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Stick to a Medication Schedule

You’ll likely take your Parkinson’s medicine often, at set times throughout the day. Keep on track and use: 

  • Pill boxes
  • Medication alarms
  • Med reminders
  • Lists
  • Apps to remind you

Taking your medicine on time, even within the hour, can prevent symptoms from getting worse.

Choose a Single Pharmacy
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Choose a Single Pharmacy

Your pharmacist is another great person to ask about your medicines and any potential side effects. Your pharmacy keeps a record of your medicines — both your prescriptions and over-the-counter ones. 

Make it easier and get all your prescriptions filled at one place. Ask your pharmacist to spot any medicines that might interact and stop trouble before it starts.

Alert Others of Your Parkinson’s and Medications
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Alert Others of Your Parkinson’s and Medications

Think about adding a medication card in your wallet along with your prescription list. The med card can alert others about your advanced Parkinson’s and key medicines for an emergency.

Your cell phone is another handy place for this information. Or you can wear a MedicAlert bracelet to let others know about your condition and any medicines.

Share Your Medication Allergies
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Share Your Medication Allergies

Tell your doctor and pharmacist about any medication allergies. They’ll make a record and check for any interactions.

Pay attention and get medical help right away if you have symptoms of a drug allergy, such as: 

  • Fever
  • Swelling
  • Rash, hives
  • Watery eyes that itch
  • Runny nose
  • Shortness of breath, wheezing

Your pharmacist can also check before you start a new medicine to make sure it isn’t a concern. 

Store Your Medicines Safely
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Store Your Medicines Safely

Here are a few ways to keep your Parkinson’s medicine safe:

  • Securely store your medicine and any others you're taking.
  • Check to make sure your medicines aren’t expired — they may not work as safely or as well.
  • Keep your medicines in the original bottle or package, so you can clearly read the label.
  • Make sure kids and pets can’t reach your medications.
Diet Adjustments for the Protein Effect
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Diet Adjustments for the Protein Effect

Sometimes the protein from your food can block your body from taking in your Parkinson’s medicine — it’s called the “protein effect.” 

More common in the later stages of Parkinson’s, the effect doesn’t happen to everyone. You may want to wait to eat protein at least 30 minutes after taking your medication. Ask your doctor how to adjust.

Preparing for Surgery and a Hospital Stay
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Preparing for Surgery and a Hospital Stay

Parkinson’s disease can sometimes cause side effects after anesthesia medicine. But you can prepare for surgery and ask for help ahead of time to keep up with your usual medication schedule.

Talk to your doctor, surgeon, or anesthesiologist about sticking to your meds in the hospital. They’ll help you plan to continue your Parkinson’s medicines in advance.

Get Support From People That Care
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Get Support From People That Care

Your friends, family, and community can help you with your late-stage Parkinson’s disease. They can help keep your medicines in order and stick to a routine.

Over time, you may find that you need more help. That’s OK. Ask your doctor for solutions as you have:

  • Trouble swallowing
  • “Off” times between medication doses
  • Challenges when you can’t move

Work closely with your care team. They’ll help you adjust and manage your medicines safely.

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SOURCES:

Mayo Clinic: “Parkinson’s disease,” “Drug Allergy.”

CDC: “Medication Safety,” “Your Prescription Medicine: Tips for Safe Storage and Disposal.”

American Parkinson’s Disease Association: “Medications to avoid (or use with caution) for people with Parkinson’s disease,” “Interactions between Levodopa and food – What to Avoid,” “Parkinson’s disease and preparing for surgery.”

FDA: “Finding and Learning about Side Effects (adverse reactions).”

Parkinson’s UK: “Managing drug treatments for Parkinson's,” “Adjusting Parkinson's medication,” “How to manage your medication.”

Hospital Pharmacy: “Delayed Administration and Contraindicated Drugs Place Hospitalized Parkinson’s Disease Patients at Risk; Doxorubicin Liposomal Mix-up; Avoid Mix-ups Between Hydroxyprogesterone and Medroxyprogesterone.”

Johns Hopkins Medicine: “The Parkinson's Caregiver: 7 Ways to Help Your Loved One,” “Medication Management and Safety Tips.”